0000034945 00000 n #PVC or polyvinyl chloride is the most common blister packaging material. Considering knurl pattern. 11/27/2012. Learn more about our packaging solutions that are flexible, adaptable and capable of handling complex pack designs at minimal cost. The die designs for solid oral dosages, especially moisture-sensitive products, have to be accurate in measurements. The product is surrounded by a clear plastic film and sits in a die-cut (cutout) area in the paperboard card. A series of blister cavities is sometimes called a blister card or blister strip as well as blister pack. It consists of one sheet folded over onto itself and sometimes fused at the edges. It is like a hybrid version of a mock clamshell with an added flat plastic backing that is glued to the blister pocket. This provides a very solid and steady platform for even the most awkward and unbalanced products. 0000011077 00000 n Both single-dose and multi-dose types exist. However, consideration also needs to be given to compatibility of base and lidding materials to guarantee seal integrity. All-Paper Blister Made completely of paper - including the blister - more of the package surface is available for full-color printing. hW[o6z0tG7K2PpI]h%qytE6}Ze[Y\?kZn,?05A For very deep draw thermoformed cavities, the triplex specifications are used: PVC/PE/PVDC, where the PE layer assists when forming deeper cavities. With the plastic blister sealed between two cards, trapped blisters are more tamper-resistant than face seal blister packages being sealed to the front of a coated card. 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Whilst pack integrity tests will verify the seal quality of the blister before it leaves the line, consideration should also be given to any processes the pack will be subjected to after this stage. In case of difficult shapes, the warm film will be physically pushed down partially into the cavity by a "plug-assist" feature. Blister packaging machine: Blister packing machines are special machines that are used as unit-dose packaging for tablets, capsules, etc. After the forming process a 250m film will have a final thickness of 50 to 100m in some deep drawn pockets. This is a very common and inexpensive blister pack style if your volumes are high enough (25K 500K). One disadvantage of platen sealing is that it can cause air to be trapped in the blister pockets. It is crucial to choose wisely between hard-temper aluminum and soft-temper aluminum. Blister packs are created by means of a form-fill-seal process at the pharmaceutical company or designated contract packer. Single-Seal Blister Card Available in a variety of seal types, a single-seal is coated and heat-sealed to a thermoformed blister part. The principal advantages of PVC are the low cost and the ease of thermoforming. Heat and sometimes vacuum is applied in order to adhere the film tightly onto the product and card. Hi Andrew, no not really, just tell your structural designer you want a hole for your product to come out of. PVDC blister films are available in 2 or 3 layer specifications referred to as duplex or triplex. In 2021, the market is growing at a . Ho@=@w8-}#A)=?6k9H~wu{/|_s=]}0&pKfi z,,}{~-UYoZzZSw[/*M?%%WRR| ,dpf4JI'pZ7t~'R&,V7'oG 8 Top Tips for achieving a Brilliant Blister Seal, Founded in 1980, Sepha has established a global reputation for innovation and development of specialised, high-quality equipment for use in the manufacture of pharmaceutical blister packs, parenterals, medical devices and healthcare products. WVTR values of commercial cyclic olefin-based pharmaceutical blister films typically range from 0.20 to 0.35 g/m2/day at 38C/90% RH. In the case of thermoforming, a plastic film or sheet is unwound from the reel and guided though a pre-heating station on the blister line which will cause the plastic to soften and become pliable. Material is certainly displaced, however it is more like an impression and is particularly useful for smaller workpieces. Email: 2023 Accupack. When the specimen of foil checked, packing shall start and initially packed medicine shall be checked for leak test. The main advantages of unit-dose blister packs over other methods of packing pharmaceutical products are the assurance of product/packaging integrity (including shelf-life) of each individual dose and the ability to create a compliance pack or calendar pack by printing the days of the week above each dose. In this configuration, the blister extends to the full size of the card as in the full face seal blister, but instead of being sealed to the card, it has flanges that wrap around the card. Due to the nature of the material and design, it makes it more cost-effective than other types of packages that are on the market. See information below. Both of which are knurling processes achieved by pressing the knurl pattern into a round workpiece. The diameter of your workpiece will change after your knurling process. In recent years, improvements in cold formingspecifically allowing steeper depth/angles during forming, which minimizes the amount of material used for each cavityhave helped this technology increase. Forming a deeper, wider impression the first time around helps to assure that the teeth will track into the initial grooves for all subsequent revolutions. Beveled edge wheels are best for forming operations. Ask about our contract packaging services! Notice how the film allows for pressure to be applied without tearing the film simply bounces back. Customers get a full 360 view of the product. Interested in learning more about the tools you will need to be successful in knurling applications? Secondary packaging: Secondary packing encloses the drugs inside the carton, bottle, etc. Polyvinylidene chloride (PVDC) can be coated onto a PVC film to obtain very high moisture and oxygen barrier properties depending on the coating weight. 'Pharmaceutical Packaging: the silent bodyguard'. 0000001431 00000 n The warm plastic will then arrive in a forming station where a large pressure (4 to 8 bar) will form the blister cavity into a negative mold. PCTFE films have the lowest water vapor permeation compared to all other plastic films used in blister packaging and have thermoforming properties similar to plain PVC though it is also the most expensive. Standard (Shape), Female Diamond Knurl Wheel. But as they say, a stitch in time and prevention is better There are certain practices and steps taken pre-packaging that will ensure the sealing success you need for all your blistering sessions. Save my name, email, and website in this browser for the next time I comment. Types of Packaging - The Blister Pack "Blister pack" is a general term that describes packaging that uses a process known as thermoforming. hhxG_}+8U"%vMTg0QYF#Mh!h&eR\~98ZoWfcKUDa&. Tertiary packing: A Tertiary is used for bulk handling of drugs like storage in a warehouse. 0000021700 00000 n biological contamination and degradation. e 0wBY`u;JwH;pt0ut4pt0t`"p!8`@BA 0j00l@y6pew_?X ,YHy$#HyC`cP/:9!&P(M @EeLZ30'@M=` The knurling head can be rotated and locked with the side bolt, allowing you to use different patterns. Determining Blank Diameter and the Number of Teeth that will be Rolled For Circular pitch knurls:Blank Dia. Blister packs refer to a variety of packaging that have a preformed plastic pocket or shell (where a product sits securely in place) that is most often heat sealed to an adhesive coated paperboard card or foil backing (think single dose pills or lozenges). emoving enough material from the workpiece to actually reduce the diameter. Blister packaging is widely used across the pharmaceutical industry as a unit-dose packaging solution that helps people take the correct amount of medication at the right time. The most basic material for the forming web is polyvinyl chloride (PVC). Many blister packaging machines use heat and pressure via a die to form the cavity or pocket from a roll or sheet of plastic. Another caveat is that micro channeling is not evident. Ideal for creating sharp corners on softer materials. Most pharmaceutical companies around the world rely on blister packs to guarantee theuniformity, purity, integrity, safety and stability of their products. x # Teeth [die]) / (Knurl Dia. + C.F.*). >#i\DbQ6sz6W&2(~yu?c4TE^\oh5a$bN)^d21KP pd1sE? Check out this video below by YouTuber and machinist Joe Pieczynski. Easy as PVC The term 'blister' encompasses several types of pre-formed plastic packaging used for small consumer goods, foods and pharmaceuticals. The first reason is aesthetic as knurling is a decorative finishing process that develops a texture on the given workpiece. Often a blister card is used (but doesnt have to be) and is inserted, not sealed as in the other styles of blister packs. 3/4 Diam, 90 Tooth Angle, 30 TPI Straight Knurl Wheel. They are used to create a raised diamond design. On a wider web, use a slightly larger knurl to allow some places for the entrapped air to go. Right-hand diagonal knurl wheels are used to produce left-hand diagonal patterns. SEPHA has established a global reputation for innovation and development of specialised, high quality equipment for use in the manufacture of pharmaceutical blister packs, medical device and healthcare products. Site Map | Terms and Conditions of Sale | Privacy Policy, 2000 - MSC Industrial Direct Co., Inc. All Rights Reserved, Ensure knurl's axis is parallel to the blanks axis, Never over roll. 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